23 Jul Use of baicalin in promoting vitro directional differentiation of mesenchymal stem cells and method thereof
Abstract
The invention provides a purpose of baicalin on promoting the directional division in vitro of mesenchymal stem cells in bone marrow. The invention also provides a method of promoting that the mesenchymal stem cells in bone marrow differentiate into liver cells in vitro. The invention adopts baicalin as cell differentiation accelerant; under the condition that fibroblast growth factor-4(FGF-4) exists, the invention induces the mesenchymal stem cells in bone marrow to directionally differentiate into liver cells. The invention also provides a purpose that mesenchymal stem cells in bone marrow in vitro uses the liver cells, which is induced and directionally divided into by baicalin, as the seed cells of liver tissue engineering and cell transplantation, or as the bio-artificial liver. The invention also provides the purpose of baicalin or the baicalin combined with the transplantation of mesenchymal stem cells in bone marrow in preparing liver diseases treating medicine as the cell differentiation accelerant; the baicalin is prepared into the medicine treating liver diseases, the transplantation of mesenchymal stem cells in bone marrow is combined to treat heavy liver disease. The invention also provides the purpose of baicalin containing cell preserving liquid in seed cells storage.
Year: 2008
Country: CN
Doc No: 101230331