Trichophyton rubrum infection model preparation method

Trichophyton rubrum infection model preparation method

Abstract

An embodiment of the invention discloses a trichophyton rubrum infection model preparation method and application. The preparation method includes the steps: separating a corium layer and a cuticularlayer of prepuce tissues, and digesting and culturing the cuticular layer to obtain human keratinocytes; finally, adding the human keratinocytes to a collagen scaffold and culturing the human keratinocytes to form a tissue engineering skin model. The model is simple to operate and easy to observe and solves the problem that a current trichophyton rubrum infection animal model is not easily observed. Seeds of the trichophyton rubrum infection model are the human keratinocytes and closer to the biological state of human skin fungal infection.

Year:  2019

Country:  CN

Doc No:  109971704

 

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