23 Jul Tissue engineering nanofiber intravascular stent and preparation method thereof
Abstract
The invention relates to a tissue engineering nanofiber intravascular stent and a preparation method thereof. The stent consists of PLCL and a degradable polymer material, and has a nanofiber structure microcosmically, and the aperture is 5-10 microns. Preparation: dissolving the PLCL and a positively charged polymer in two different solvents to obtain homogeneous solutions, after dissolving completely, mixing two solution systems evenly, and performing electrostatic spinning by using a roller as a receiving device to obtain a nanofiber stent; and performing self-assembly modification by using a negatively charged degradable polymer as a surface modifier, washing by using deionized water, and drying to obtain a porous fiber stent. According to the tissue engineering nanofiber intravascular stent, the material is improved to improve the anticoagulant performance of the intravascular stent through performing self-assembly modification on a surface of the stent.
Year: 2017
Country: CN
Doc No: 107296979