23 Jul Tissue engineering meniscus composite scaffold and preparation method thereof
Abstract
The invention discloses a tissue engineering meniscus composite scaffold and a preparation method thereof. The scaffold comprises: a C-shape bracket which is consistent with the initial shape of meniscus to be regenerated and repaired, the bracket comprising a plurality of first degradable polymer material fibers extending in a circumferential direction of the bracket and a plurality of second degradable polymer material fibers extending in a radial direction of the bracket, the first degradable polymer material fiber and the second degradable polymer material fiber being arranged in a multilayer cross arrangement to form a frame structure having a plurality of first pores; a matrix material composited within a plurality of first apertures of the stent to form a meniscus composite stent having a plurality of second apertures. The meniscus composite scaffold provided by the invention has excellent mechanical properties and biocompatibility, and can provide an excellent microenvironmentrequired for cell growth, thereby enabling the newborn meniscus to have excellent shape, structure, mechanical properties and physiological functions.
Year: 2019
Country: CN
Doc No: 109199649