23 Jul Tissue engineering lung tissue and construction method thereof
Abstract
The invention discloses a tissue engineering lung tissue and a construction method thereof, belonging to the field of tissue engineering and regenerative medicine. The tissue engineering lung tissue is obtained with the following construction method: (1) preparing lung cell suspension; (2) preparing sodium alginate-polylysine-alginate microcapsules; (3) compounding cells with holder material, and cultivating cell and holder composite. The invention adopts sodium alginate-polylysine-alginate microcapsules and combines liquid state I type collagen with Matrigel matrigel to serve as the holder of tissue engineering lungs; the holder system can effectively accelerate the formation of the alveolus pulmonis type structure to realize the exchange of air and nutritive materials, so that the invention has important significance for clinically applying tissue engineering lung tissues to treat patients with lung diseases in the future. The construction method of the invention has simple technology and moderate application condition.
Year: 2010
Country: CN
Doc No: 101701208