23 Jul Tissue engineering induction scaffold for peripheral nerve repair
Abstract
The utility model discloses a tissue engineering induction scaffold for peripheral nerve repair. Bracket body, the support body is composed of an outer structure layer and an inner structure layer. The outer structural layer and the inner structural layer are connected through Van der Waals’ force. through convection holes are formed in the outer structure layer and the inner structure layer; an induction channel with a honeycomb-shaped cross section is arranged in a cavity of the inner structure layer of the stent body; an exchange hole is formed in the channel wall of each sub-channel of theinduction channel; the exchange holes and the convection holes are located in the same plane, adsorption grooves are formed in the inner wall of the induction channel, NGF microspheres are adsorbed on the adsorption grooves, and the distance between the adsorption grooves of the induction channel is sequentially divided into a first microsphere sparse section, a microsphere dense section and a second microsphere sparse section from left to right. The stent can overcome the influence of the’growth factor oasis’ effect on the growth of the axons from the far end to the near end, and meanwhile,the constructed honeycomb-shaped induction channels can form growth constraints on the axons, so that the axons are prevented from being twisted and disordered due to disordered growth.
Year: 2019
Country: CN
Doc No: 208942483