23 Jul Tissue engineering cartilage stent and method for preparing same
Abstract
The invention discloses a tissue engineering cartilage stent and a method for preparing the same. The method includes a step A, extracting II-type collagen; a step B, preparing a primary CII-HA-CS-HAP three-dimensional cartilage stent by the aid of the II-type collagen, hyaluronic acid, chondroitin sulfate and hydroxyapatite; a step C, crosslinking the primary CII-HA-CS-HAP three-dimensional cartilage stent by the aid of an EDC/NHS system and freezing and drying the CII-HA-HAP three-dimensional cartilage stent to obtain the CII-HA-CS-HAP three-dimensional tissue engineering cartilage stent. The tissue engineering cartilage stent and the method have the advantages that the tissue engineering cartilage stent is excellent in biocompatibility, low in toxicity and easy to degrade, and degradation products are nontoxic; the tissue engineering cartilage stent is compact in appearance, and various performance parameters are adaptive to repairing cartilage tissues of human bodies; the constructed tissue engineering cartilage stent is made of wide material sources and easy to shape, and can be used for repairing wide-area wound, and the like.
Year: 2015
Country: CN
Doc No: 105031724