23 Jul Tissue engineering acellular vascular scaffold preparation method
Abstract
The invention belongs to the field of medical equipment, and more specifically relates to a tissue engineering acellular vascular scaffold preparation method. The method comprises the following steps:1) preparing a spinning fiber skeleton; winding the spinning fibers through a spinning technology at a receiver, and interlacing the spinning fibers up and down to form a cylindrical structure; 2) implanting the spinning fiber skeleton obtained in the step 1) under animal skin, and finally forming the host cell and extracellular matrix-coated tissue engineering vascular scaffold; and 3) removingthe receiver, and removing cells of the tissue engineering vascular scaffold. The constructed fiber skeleton is moved under the animal skin, the tissue vascular scaffold formed by migration cells dueto an immunization mechanism is constructed in the host animal body, accellular processing is carried out, the netted scaffold is kept, the blood vessel mechanical properties can be improved, an immunization reaction after transplantation can be reduced, the extracellular matrix is fully used, and good environment is provided for cell regeneration.
Year: 2018
Country: CN
Doc No: 108434519