23 Jul Tissue engineered composite skin and preparing method thereof
Abstract
The present invention relates to a tissue engineering composite skin, including cuticular layer and dermal layer, said cuticular layer is stratified, and is formed from cuticular stem cell which is continuously proliferated and differentiated, and includes basal layer formed from cuticular stem cell and several layers of tissue formed from keratinocytes differentiated and positioned on the basal layer. The dermal layer is formed from scaffold material of polyglycollic acid, etc. (the biological scaffold material also includes cell dermal matrix, callogen gell and polylactic acid (PLA), etc.) and fibroblast and its secretory matrix. Said invented composite skin can be used for directly covering surface of wound and repairing defect of skin. Said invention also relates to its preparation method.
Year: 2004
Country: CN
Doc No: 1528253