23 Jul THERAPEUTIC AGENT FOR OPHTHALMIC DISEASES CONTAINING RETINAL PIGMENT EPITHELIAL CELL GROWTH FACTOR AS AN ACTIVE INGREDIENT
Abstract
PURPOSE: To provide a therapeutic agent for ophthalmic diseases, which contains retinal pigment epithelial cell growth factor as an active ingredient, thus is useful for treating retinal pigment degeneration, retinopathy, yellow spot disease, retinal detachment and the like. CONSTITUTION: This therapeutic agent contains retinal pigment epithelial cell growth factor (preferably tissue factor pathway inhibitor-2 or placental protein 5) as an active ingredient. This factor is generally obtained by isolation and purification from human culture cell supernatant, or from isolation and purification from the extract from cells or from the supernatant of the cells prepared by the genetic engineering. The human culture cells are preferably, for example, epithelial cells, stroma cell or fibroblast cells. The dose of this factor is preferably 0.1-10mg/each adult.
Year: 1996
Country: JP
Doc No: H08104700