Temperature response type injectable hydrogel and preparation method and usage thereof

Temperature response type injectable hydrogel and preparation method and usage thereof

Abstract

The invention relates to a temperature response type injectable hydrogel and a preparation method and the usage of the injectable hydrogel; the hydrogel comprises component A, component B and water, wherein the component A is cholesterol-polyethylene glycol-cholesterol; and the component B is amination beta cyclodextrin graft hydroformylation glucan. The preparation process of the injectable hydrogel is simple and convenient, and the prepared injectable hydrogel has a certain strength and toughness as well as self-repairability; compared with the prior art, the invention improves the controllability of the performances of the hydrogel, and further improves the biocompatibility of the hydrogel; the hydrogel prepared by the invention has biodegradability and can be etabolized by human body; and the hydrogel has temperature responsiveness and injectability, and can be used for a drug carrier, embolism material and tissue engineering material.

Year:  2012

Country:  CN

Doc No:  102827446

 

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