23 Jul SYSTEMS AND METHODS FOR TREATING AND CONDITIONING SMALL VOLUME LIQUID SAMPLES
Abstract
Systems and methods are for creating liquid toroidal mixing patterns within microliter volumes of liquids are contemplated. An electrode geometry comprising peripheral electrodes defining an annular configuration and interior electrodes are contemplated, to which an alternating current may be applied. Via control of the frequency, waveform, amplitude and bias of the current, liquids and the components of those liquids may be mixed in a toroidal motion. This same electrode geometry may also be used to accomplish the deposition of targeted materials onto the surface of the peripheral or interior electrode by further manipulating the frequency, amplitude, and bias of the waveform of the applied current. Methods of applying such techniques are also contemplated in the context of blood typing assays, latex agglutination assays, micro array assays, transfection, transduction, and tissue engineering methods, and it may be seen that such techniques may result in substantial benefits.
Year: 2020
Country: US
Doc No: 2020114323