23 Jul System for the manufacture of tissue engineered blood vessels
Abstract
This invention relates to a system for the manufacture of a tissue engineering blood vessels (TEBV) made from a cultured fibroblast sheet rolled into a multilayer vessel which has sufficient burst strength to withstand physiological blood pressure without the inclusion of smooth muscle cells or synthetic scaffolding. The TEBV is made in a bioreactor system comprising at least one module that contains a cultured tissue sheet, first mandrel onto which said tissue sheet is rolled, a motion control device into which said first mandrel is fitted and a clamping device for securing the tissue sheet onto the first mandrel.
Year: 2011
Country: EP
Doc No: 2275153