23 Jul Synthesizing process and use of unsaturation cyclic aliphatic carbonate monomer and its polymer
Abstract
This invention involves unsaturated cyclic aliphatic carbonate monomer and polymer synthesis and uses, and is biomedical polymer materials. From 2,2 – dimethylolpropionic acid departing, to synthesize 2-methyl-2-allyl-oxygen carbonyl trimethylene carbonate and 2-methyl-2-propargyl oxygen carbonyl trimethylene carbonate, and then through ring-opening polymerization or aliphatic monomers cycloate monomer opening loop and copolymerization, gain copolymer of aliphatic polycarbonate or aliphatic polyester-carbonate that side group contains double and Triple bond. Such polymer has advantage of both aliphatic polyester and carbonate, is biodegradable, degradation products is non-toxic. Use the functional side group of Double and Triple bond can connect drugs, active peptides or other bioactive elements with the polymer, improving the biocompatibility and biological activity of polymer, which may has real application in controlled-release drug, polymer pro-drug and tissue engineering fields.
Year: 2007
Country: CN
Doc No: 100999515