23 Jul Stretch-electricity combinational stimulation cell culture device
Abstract
The invention discloses a stretch-electricity combinational stimulation cell culture device. The device comprises a cell culture box, a cell culture cavity fixing frame, a cell culture cavity, a stepper motor and a signal generator, wherein the culture box is provided with a porous channel communicated with outside; the cell culture cavity is fixed in the cell culture cavity fixing frame; the cell culture cavity comprises a fixed threaded rod, a groove body, a fixed clamping apparatus, an elastic membrane, a sliding clamping apparatus and a sliding threaded rod; the elastic membrane is fixed on the fixed clamping apparatus and the sliding clamping apparatus; the fixed clamping apparatus is connected with the fixed threaded rod; the sliding clamping apparatus is connected with the sliding threaded rod; the fixed clamping apparatus, the elastic membrane and the sliding clamping apparatus are positioned in the groove body; the sliding threaded rod is connected with the stepper motor; andthe signal generator is connected with a metal electrode in the cell culture cavity. The stretch-electricity combinational stimulation cell culture device overcomes the disadvantage of incapacity of simulating a physical microenvironment in which internal cells are subject to stretching force and electric stimulation at the same time in the conventional method, establishes a cell culture method under the condition of combining stretching force stimulation with electricity stimulation, and promotes the development of cell and tissue culture methods and related tissue engineering reactors.
Year: 2010
Country: CN
Doc No: 101892152