23 Jul SOLUTION SPRAY PREPARATION METHOD FOR SCAFFOLD FOR ACTIVE BIOLOGICAL TISSUE ENGINEERING
Abstract
A solution spray preparation method for a scaffold for active biological tissue engineering, comprising the following steps: (1) dissolving a biomedical material to obtain a biomedical material aqueous solution having a concentration of 2-50%; (2) adding an immunoglobulin solution to the biomedical material aqueous solution prepared in step (1) to prepare an active spinning solution; (3) using a high-pressure air jet stream having a temperature of 0-37°C for drawing power to perform solution spray spinning, and using a spinning receiver to receive spinning; (4) providing a cell printing device behind a fiber receiver, and printing an active solution containing seed cells or cell growth factors onto a fiber membrane prepared in step (3) so as to finally prepare the scaffold for active biological tissue engineering. The scaffold for active biological tissue engineering prepared by using the described preparation method may, after suitable in vitro cultivation, be implanted into the human body as a scaffold for biological tissue engineering, or be used as a scaffold for skin tissue engineering to promote wound healing.
Year: 2020
Country: WO
Doc No: 2020134445