23 Jul Small-diameter tissue engineering artificial blood vessel and preparation method thereof
Abstract
The invention discloses a minorcaliber tissue engineering artificial vessel. The excised extract cell umbilical vessel is taken as a bracket, the gap part of the bracket is filled with smooth muscle cells and mechanocyte; the endothelial progenitor cells or mesenchymal stem cells are planted in the surface of the inner wall of the excised extract cell umbilical vessel. The minorcaliber tissue engineering artificial vessel has good biocompatibility and has the abilities of inducing, supporting and maintaining cell functions, thus reducing the reciprocal infection of virus among seeds. The artificial vessel produced by the invention overcomes the problem that the supply of autologous vessel plantation is limited and the failure problem of the synthesized implants for formation of thrombosis and/or endometrial hyperplasia, thus improving the long transplantation patency that the minorcaliber tissue engineering artificial vessel is planted into human body, leading the sufferers to avoid a secondary operation. The raw materials of the artificial vessel are obtained easily, the preparation method is simple, and cost is low, thus being accepted by the sufferers and having vast social benefit and economic benefit.
Year: 2008
Country: CN
Doc No: 101318032