23 Jul Small-caliber bionic blood vessel with three-layer structure and manufacturing method thereof
Abstract
The invention discloses a small-caliber bionic blood vessel with a three-layer structure and a manufacturing method thereof. Knitted silk fiber is adopted as an inner layer of the bionic blood vesselto simulate the structure and properties of human body blood vessel collagen, electrostatic spun polyurethane fiber serves as an outer layer to simulate the structure and properties of blood vessel elastin. In addition, polyacrylamide hydrophilic gel is also adopted as a middle layer to further improve the elasticity of the bionic blood vessel, meanwhile improve the bursting pressure of the bionicblood vessel and prevent blood permeation in the use process. The microcosmic three-layer structure of the human blood vessel can be simulated, and the special nonlinear mechanical properties of thehuman blood vessel can be also simulated. In addition, the raw materials for the bionic blood vessel have good cytocompatibility, are degradable and are suitable for blood vessel repair and regeneration in tissue engineering. Therefore, the small-caliber bionic blood vessel with the three-layer structure has a high potential practical value.
Year: 2018
Country: CN
Doc No: 108938143