23 Jul Simulation method for growth of bone in porous bracket based on immune regulation
Abstract
The invention discloses a simulation method for growth of a bone in a porous bracket based on immune regulation. The method comprises the following steps of S10, establishing a three-dimensional geometric model, determining a calculating area of the simulated model; introducing a porous bracket three-dimensional structure into the three-dimensional geometric model, and setting the bracket area andthe hole area for simulation calculation; S20, based on the porous bracket three-dimensional structure, calculating an immunization regulation-and-control model; S30, setting a simulation initial parameter which comprises simulation time; S40, calculating a cytokine and growth factor model, calculating a cell life motion model, calculating a blood vessel growth model, and calculating an oxygen diffusion model; and S50, determining whether a simulation time end point is reached, if not, returning to the step S40; and if yes, ending the simulation and obtaining a simulation result. The simulation method for growth of the bone in the porous bracket based on immune regulation settles problems of high animal experiment cost, and high difficulty in performing systematical and comprehensive researching in a bone tissue engineering field.
Year: 2019
Country: CN
Doc No: 110379518