23 Jul Silk fibroin porous material and preparation method thereof and tissue engineering stent
Abstract
The invention discloses a preparation method of a silk fibroin porous material, which comprises the following steps: drying a silk fibroin aqueous solution into a silk fibroin membrane, dissolving the silk fibroin membrane into water; repeating the drying-dissolving process to obtain a silk fibroin nano-wire aqueous solution; performing freeze drying of the silk fibroin nano-wire aqueous solution to obtain a silk fibroin material precursor; performing alcohol treatment or vacuum water treatment of the silk fibroin material precursor, drying to obtain the silk fibroin porous material. Compared with the prior art, the preparation method of the invention regulates the nano-structure by the self-assembly behavior of silk fibroin, that is, during multiple drying-dissolving processes, the internal nano-sphere structure of the silk fibroin aqueous solution is self-assembled into a nano-wire structure, which effectively inhibits the formation of a sheet structure; the prepared silk fibroin porous material has a nano-fiber structure, and a high porosity.
Year: 2012
Country: CN
Doc No: 102357264