23 Jul SELF-HEALING HYDROGEL AND USE THEREOF
Abstract
The present invention relates to a glycol chitosan-based hydrogel containing only natural polysaccharides without use of a toxic crosslinking agent. The hydrogel of the present invention exhibits a self-healing behavior under physiological conditions and in the presence of iron oxide nanoparticles, and thus can be useful for use as a delivery system for injection. In addition, in the hydrogel of the present invention, a delivery rate or amount of a substance carried within the hydrogel can be regulated using the magnetic field, which allows the hydrogel to be used for a variety of drug delivery and tissue engineering applications with on-demand release of gel payloads under external magnetic stimulation. The hydrogel can be effectively used as a delivery vehicle for a physiologically active substance such as a therapeutic agent.
Year: 2019
Country: US
Doc No: 2019298852