23 Jul Retrovirus carrier of bone morphogenetic protein 4 gene and its use
Abstract
The invention relates to the bone tissue gene engineering technical sphere, which in detail to recombinant vector of bone formation protein gene 4, the virus granule which converted and packed by said vector and preparing tissue engineering bone by applying the virus granule and its application. The invention is characterized in that: successfully constructing pLEGFP-hBMP-4 reverse transcript viral vectors by taking pLEGFP as the reverse transcript viral vectors; getting LEGFP-hBMP-4 and LEGP reverse transcript viral vectors by packing the cell PA317; constructing tissue engineering bone by using the marrow base cell modified by gene hBMP-4 as the seed cell.
Year: 2005
Country: CN
Doc No: 1664108