Recombination human collagen and biological synthesis method thereof

Recombination human collagen and biological synthesis method thereof

Abstract

The present invention discloses one kind of recombinant analogous human collagen and its biological synthesis process. The recombinant analogous human collagen consists of one collagen region and one non-collagen region. The non-collagen region in the carboxyl group end of the collagen region has one amino acid sequence originated the minor fibrin of T4 bacteriophage and as shown in SEQ ID No. 3, and the collagen region has the amino acid sequence shown in SEQ ID No. 2. The recombinant analogous human collagen has relatively high heat stability, high hydrophilicity, high biocompatibility, heat denaturation temperature and heat decomposition temperature higher than that of natural collagen, and stable structure. It may be applied widely in biomedicine material, tissue engineering, cosmetics, food and other fields.

Year:  2008

Country:  CN

Doc No:  101148479

 

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