23 Jul Rare-earth nucleoside fluorescent hydrogel as well as preparation method and application thereof in fluorescent encoding
Abstract
The invention discloses rare-earth nucleoside fluorescent hydrogel as well as a preparation method and application thereof in fluorescent encoding. The preparation method of the rare-earth nucleosidefluorescent hydrogel comprises the following steps: (1) preparing a soluble rare-earth nitrate water solution and a nucleoside water solution; (2) uniformly mixing the soluble rare-earth nitrate watersolution and the nucleoside water solution and regulating the pH (Potential of Hydrogen) value to 7 to 9; raising the temperature to 55 to 95 DEG C and standing and reacting for 10 to 20min; coolingto room temperature and standing for 1 to 4h to obtain the rare-earth nucleoside fluorescent hydrogel with different fluorescent colors. The rare-earth nucleoside fluorescent hydrogel disclosed by theinvention has the advantages of environment-friendly and safe raw materials, simplicity in operation, low cost and good repeatability; the rare-earth nucleoside fluorescent hydrogel disclosed by theinvention keeps characteristic of emission fluorescent light of rare-earth ions and also has characteristics of good biocompatibility of biological small molecular nucleoside, biodegradability, no toxicity and the like. The obtained fluorescent hydrogel is regulated and controlled to obtain various fluorescent colors and can be used as a fluorescent encoding material; the fluorescent hydrogel canbe used for fluorescent biological detection, cell culture and tissue engineering.
Year: 2018
Country: CN
Doc No: 108525616