23 Jul RAPID PREPARATION OF STEM CELL MATRICES FOR USE IN TISSUE AND ORGAN TREATMENT AND REPAIR
Abstract
The present invention describes a rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair. Compared with previous tissue engineering materials, the stem cell- matrix compositions of the prestn invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may behomogeneous, heterrogeneou s, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions as described provide point of service utility for the practitioner, wherin the stem cells and matrix can be combined not long befo re use, therby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
Year: 2002
Country: CA
Doc No: 2438904