23 Jul Protein sericin gel based on transformation of human platelet derived growth factor gene silk and preparation method and application of protein sericin gel
Abstract
The invention discloses a protein sericin gel based on transformation of human platelet derived growth factor (PDGF-BB) gene silk and a preparation method and application of the protein sericin gel. By using the functional silk of the human-derived PDGF-BB, sericin with the active PDGF-BB protein is extracted, a gelling reaction of the sericin is induced at the low temperature, the prepared protein sericin gel is good in mechanical property, degradable and good in cell compatibility and does not have toxicity, the PDGF-BB can stably exist, apoptosis cannot be caused, the obvious cellular inflammatory response cannot be caused, and the sericin gel biological material with a function of improving the cell proliferation activity can be applied to the tissue engineering.
Year: 2019
Country: CN
Doc No: 110354307