PROGENITOR CELL POPULATIONS, EXPANSION THEREOF, AND GROWTH OF NON-HEMATOPOIETIC CELL TYPES AND TISSUES THEREFROM

PROGENITOR CELL POPULATIONS, EXPANSION THEREOF, AND GROWTH OF NON-HEMATOPOIETIC CELL TYPES AND TISSUES THEREFROM

Abstract

Described is a method of expanding human progenitor cells by suspension culturing under non-static conditions. The culturing method provides a three-dimensional space for the rapid expansion of desirable progenitors. By this method, a new compartment of multipotential progenitor cells has been identified, which give rise under differentiation conditions to progeny including osteoblasts, chondrocytes, myoblasts, adipocytes, and other non-hematopoietic cell types. Their use in cell and tissue-based engineering is described.

Year:  2002

Country:  WO

Doc No:  2086104

 

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