23 Jul PREPARATION OF FIBRIN GEL FOR USE AS IMPLANT SYSTEM
Abstract
The present invention aims to generate a fibrin gel for cell proliferation and transport using the patient’s own blood or compatible blood. The gel-preparation process consists in taking a quantity of blood from the patient, using sodium citrate as anticoagulant, separating off the citrated plasma by centrifugation, and resuspending the cells to be transported in the plasma. CaCl2 is added to the resulting suspension to form the gel (either as an isolated coagulate or within a porous chitosan, gelatin or hyaluronic acid matrix), and the gel is cultured in an incubator to promote cell growth. The invention will be of use in cell growth for the purposes of implantation in cutaneous, cartilaginous, gingival and bone lesions, inter alias, and in the field of tissue engineering.
Year: 2014
Country: US
Doc No: 2014242181