23 Jul Preparation method, raw material, product and application of photo-crosslinking hydrogel material
Abstract
The invention provides a preparation method, a raw material, a product and an application of a photo-crosslinking hydrogel material. The preparation method comprises the steps of dissolving a component A, namely a photosensitive high polymer derivative, in a biocompatible medium to obtain a photosensitive high polymer solution A, dissolving a component B, namely a photoinitiator, in the biocompatible medium to obtain a photoinitiator solution B, dissolving a component C, namely other biocompatible high polymer derivative, in the biocompatible medium to obtain a high polymer solution C, uniformly mixing the solution A and the solution B (or adding the solution C) to obtain a hydrogel precursor solution, and illuminating the hydrogel precursor solution under a light source for photo-crosslinking to obtain hydrogel. A hydrogel system has the characteristics of high photocuring speed, strong tissue adhesion, excellent mechanical properties, good biocompatibility, excellent clinical operability and the like. The invention further provides a reagent kit for preparing the hydrogel, and the application of the hydrogel material to tissue engineering, regeneration medicine and 3D printing and as a cell, protein or drug carrier.
Year: 2019
Country: CN
Doc No: 109776451