23 Jul Preparation method of thermosetting elastomer tissue engineering scaffold with multi-level porous structure
Abstract
The invention relates to a preparation method of a thermosetting elastomer tissue engineering scaffold with a multi-level porous structure. The preparation method comprises the following steps of: (1) mixing a thermosetting material with a filling material to obtain a mixed material; establishing a model of a cuboid netty structure by means of CAD (Computer Aided Design) software; and then adding the mixed material into a heating cavity of a 3D printer and performing 3D printing to obtain an initial scaffold; and (2) performing thermal crosslinking or optical crosslinking on the initial scaffold in the step (1) to obtain the thermosetting elastomer tissue engineering scaffold; and finally, removing the filling material to obtain the thermosetting elastomer tissue engineering scaffold with the multi-level porous structure. The invention solves the fundamental problem of directly printing thermosetting material by thermoplastic FDM (Fused Deposition Modeling), and the prepared tissue engineering scaffold has the multi-level porous structure which is controllable in precision in structure. The method is simple and convenient and suitable for various biological materials and has a good application prospect.
Year: 2017
Country: CN
Doc No: 107137775