23 Jul Preparation method of thermo-sensitive hydrogel by taking baicalin as template
Abstract
The invention discloses a preparation method of thermo-sensitive hydrogel by taking baicalin as a template. The hydrogel is prepared from the baicalin, thermo-sensitive monomers, a chemical cross-linking agent, an initiator and an organic solvent according to the ratio by weight percent of (0.1-0.9%):(5-10%):(0.85-5%):(0.05-0.1%):(84-94%). The preparation method comprises the following steps: 1) dissolving the baicalin in the organic solvent; 2) sequentially adding the thermo-sensitive monomers, the chemical cross-linking agent and the initiator into mixed solution in the step 1), and performing free radical polymerization at high temperature after sealing to get yellow gel; and 3) cutting the yellow gel into pieces, soaking and removing impurities. The product according to the invention has thermo-sensitive property, the baicalin plays a role of the template in the gel, the pore size, the thermo-sensitive property and the mechanical properties of the product can be regulated through the using amount of the baicalin, and the product can be used in biological medicine, tissue engineering, protection against drought, anti-waterlogging property, chemical separation and other fields.
Year: 2012
Country: CN
Doc No: 102391415