23 Jul Preparation method of temperature-sensitive cellulose quaternary ammonium salt/beta-sodium glycerophosphate hydrogel
Abstract
The invention which discloses a preparation method of a temperature-sensitive cellulose quaternary ammonium salt/beta-sodium glycerophosphate hydrogel belongs to fields of the biological technology and tissue engineering. A 10-60wt% sodium glycerophosphate solution is added to a 1.5-5.5wt% cellulose quaternary ammonium salt solution drop by drop at 0-20DEG C to prepare a cellulose quaternary ammonium salt/beta-sodium glycerophosphate mixed solution, and the mixed solution is rapidly cured at the body temperature to form the hydrogel. The liquid state of the cellulose quaternary ammonium salt/beta-sodium glycerophosphate solution can be maintained at room temperature, so it is very convenient to add cells, proteins, enzymes and therapeutic medicines to the solution, thereby the obtained solution can be used as a cytoskeleton material or a medicine carrier. The cellulose derivative which has very good biological compatibility is very suitable for the fields of the biological technology and tissue engineering.
Year: 2012
Country: CN
Doc No: 102432895