Preparation method of silk fibroin-poly(hydroxybutyrate-hydroxyvalerate) composite fiber membrane

Preparation method of silk fibroin-poly(hydroxybutyrate-hydroxyvalerate) composite fiber membrane

Abstract

The invention discloses a preparation method of a silk fibroin-poly(hydroxybutyrate-hydroxyvalerate) composite fiber membrane, which comprises the steps of: mixing a prepared silk fibroin solution with a poly(hydroxybutyrate-hydroxyvalerate) solution to prepare a spinning solution, and conducting electrostatic spinning and aftertreatment. Based on the electrostatic spinning method, the composite fiber membrane is prepared, and the fiber membrane has good biocompatibility of the silk fibroin and the excellent mechanical performance of the poly(hydroxybutyrate-hydroxyvalerate) simultaneously, is more applicable to the biomedical field, and is expected to be used as a material for engineering of skin, nerves and cartilaginous tissues. The prepared composite fiber membrane has higher porosity, good mechanical performance, good air permeability and moisture permeability and large liquid absorption amount, can be degraded in human body and can promote tissue repair; and the preparation method has simple process.

Year:  2011

Country:  CN

Doc No:  102102278

 

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