23 Jul Preparation method of self-repaired polyurethane hydrogel based on double-selenium dynamic covalent bond
Abstract
The invention discloses a preparation method of self-repaired polyurethane hydrogel based on a double-selenium dynamic covalent bond. The hydrogel is obtained by performing condensation and cross-linking reaction for diisocyanate, polyethylene glycol, double-selenium diol and diethanol amine and then immersing in deionized water. The hydrogel is based on the visible light dynamic reversibility of the double-selenium bond, the self-repairing for the damage can be realized under the radiation of moderate visible light, and good mechanical performance can still be kept by virtue of multiple repeated repairing. The hydrogel is a polyurethane structure, the polyethylene glycol is used as a hydrophilic soft section, the biological compatibility and the molecular structure designability are good, the mechanical performance can be effectively adjusted by adjusting a ratio of a soft section to a hard section of a molecular chain, and the requirements of the real application can be better met, so that the application prospect in the field of biological tissue engineering is wide.
Year: 2017
Country: CN
Doc No: 106750115