23 Jul Preparation method of PRP (platelet-rich plasma)/MSCs (marrow stromal cells)/oyster shell bone tissue scaffold material
Abstract
Disclosed is a preparation method of a PRP (platelet-rich plasma)/MSCs (marrow stromal cells)/oyster shell bone tissue scaffold material.A tissue engineering bone is constructed by taking oyster calcium carbonate as a scaffold, MSCs as seed cells and a PRP as an endogenous growth factor.The preparation method is simple and convenient.The tissue engineering bone, constructed by taking oyster shell as a scaffold, the marrow stromal cells as the seed cells and the platelet-rich plasma as the endogenous growth factor, is excellent in bone defect repairing effect and is similar to an autogenous bone graft, thereby being a satisfactory bone graft substitute material.A membrane-scaffold complex formed by wrapping the oyster shell scaffold by a membrane has excellent physical, chemical and mechanical properties, and is excellent in ectopic bone formation capability and biocompatibility, good in adhesive capacity for cells, capable of keeping normal growth, differentiation, proliferation and synthesizing and secreting functions and proper in biodegradation rate, and the materials and degradation products thereof have no toxic and side effect on organisms.
Year: 2016
Country: CN
Doc No: 105749348