23 Jul Preparation method of porous fiber with controllable degradation rate for tissue engineering scaffold
Abstract
The invention relates to a preparation method of porous fiber with a controllable degradation rate for a tissue engineering scaffold, which comprises the following steps: uniformly mixing a biodegradable polymer and a pore-forming agent, vacuum drying, melt spinning, drawing, immersing into hydrochloric acid or distilled water to remove the pore-forming agent, and vacuum drying, thereby obtainingthe porous fiber with micro pores with the diameters of 10-100mum uniformly distributed on the surface thereof. The preparation method of the invention is simple and is applicable to industrial production. The diameters of the micro pores of the prepared fiber are matched with cell sizes, so that cells can be easily adhered into the micro pores on the surface of the fiber for growth. Simultaneously, the degradation rate is controllable.
Year: 2010
Country: CN
Doc No: 101781815