23 Jul Preparation method of ordered scaffold employing thermal bonding curing of polylactic acid melt spinning fiber
Abstract
The invention discloses a preparation method of an ordered scaffold employing thermal bonding curing of a polylactic acid melt spinning fiber. The method comprises the following steps: preparing a melt spinning fiber from polylactic acid (PLA) slices with good biodegradability and biocompatibility by a melt spinning method; preparing fiber assemblies which are arranged in parallel by a winding process; and forming an ordered scaffold with a stable structure by PLA fiber assemblies which are loose and are arranged in parallel by a thermal bonding curing manner. The ordered scaffold produced by the PLA melt spinning fiber prepared by the method is stable in structure, and has a relatively good internal hole structure, physical property and mechanical property; and the ordered scaffold can be applied to the biomedical fields of bone tissue engineering and the like, and has relatively good application potential and prospect. According to the preparation method, a reference can be provided for preparation of similar structure brackets employing the melt spinning fibers of other high polymers, such as polycaprolactone, polyglycolic acid and polyurethane.
Year: 2015
Country: CN
Doc No: 104667343