23 Jul Preparation method of novel neural restoration tissue engineering scaffold
Abstract
The invention relates to the technical field of biological composite materials, and discloses a preparation method of a novel neural restoration tissue engineering scaffold. The preparation method comprises the following steps: modifying bacterial cellulose; preparing a living cell derived material; uniformly mixing the modified bacterial cellulose with the living cell derived material to obtain a mixture, injecting the mixture into a mold, and preparing the neural restoration tissue engineering scaffold by an ice crystals directional solidification method and a freeze vacuum drying method. The preparation method has the benefits that due to dual bionic design of a structure and a component, the living cell derived material, modified nano fibers and a conductive nano material are combined, so that the obtained scaffold is high in moisture content, good in comprehensive mechanical property and high in stability, and has bioactivity and electroactivity; meanwhile, growth and increment of blood cells can be promoted favorably, and a function of axonal regeneration can be guided; the preparation method is simple, and the shape and the size of a prepared product are easy to control; various requirements of the neural restoration tissue engineering scaffold can be met, and the application prospect is wide.
Year: 2016
Country: CN
Doc No: 105854077