23 Jul Preparation method of medical PLLA (poly-l-lactic acid) melt-spun fibers
Abstract
The invention discloses a preparation method of medical PLLA (poly-l-lactic acid) melt-spun fibers. The preparation method comprises steps as follows: medical PLLA with good biodegradability and biocompatibility is sliced, dried, extruded by a screw extruder with a single-orifice plate, a 36-orifice plate or a 24-orifice plate for melt spinning and drafting winding, and the medical PLLA melt-spun fibers are prepared. The medical PLLA melt-spun fibers prepared with the method has smaller fiber diameter, smooth surface, circular cross section and higher melting point. The medical PLLA melt-spun fibers have better application prospect, can be used for simulating the fiber network structure in an ECM (extracellular matrix), and can be used for preparing fiber scaffolds applied to tissue engineering as well as woven fabric and knitted fabric scaffolds applied to blood vessels, nerves, ligaments, muscle, knees, tendons, bone tissue engineering, drug release and loading and the like.
Year: 2016
Country: CN
Doc No: 105970315