23 Jul Preparation method of luminescent collagen polypeptide-lanthanide-series metal composite nanomaterial with cell adhesion function
Abstract
The invention discloses a preparation method of a luminescent collagen polypeptide-lanthanide-series metal composite nanomaterial with cell adhesion function. The preparation method includes the steps: (1) design of collagen polypeptide; (2) synthesis of collagen polypeptide; (3) preparation of a collagen polypeptide-lanthanide-series metal composite nanomaterial; (4) luminescent properties of thecomposite nanomaterial; and (5) cell adhesion function of the composite nanomaterial. The used collagen polypeptide can self-assemble to form a nanofiber material with similar microstructure to natural collagen under the mediation of lanthanide-series metal ions under a condition of wide range of pH. The composite fiber material not only has excellent luminescent properties, but also exhibits good cell adhesion function, provides a new strategy for the structure and function of biomimetic natural collagen and has great development potential in tissue engineering and regenerative medicine.
Year: 2019
Country: CN
Doc No: 110129252