Preparation method of in-vivo hemostatic dressing which takes transglutaminase as cross-linking agent

Preparation method of in-vivo hemostatic dressing which takes transglutaminase as cross-linking agent

Abstract

The invention discloses a preparation method of an in-vivo hemostatic dressing. The preparation method comprises the following steps: after adding the transglutaminase in a human-like collagen solution for cross linking, accurately cooling and pre-freezing through a set cooling speed, carrying out vacuum freeze drying, then carrying out Co60 irradiation sterilizing, and finally obtaining the in-vivo hemostatic dressing. The in-vivo hemostatic dressing prepared by the preparation method disclosed by the invention is high in safety, good in biocompatibility and remarkable in hemostatic effect, can be used for all kinds of wound hemostasis and postoperation hemostasis and has a good application prospect in related fields of medical biomaterials, tissue engineering and the like.

Year:  2017

Country:  CN

Doc No:  106729957

 

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