23 Jul Preparation method of composite cavity microfibers based on micro-fluidic technology
Abstract
The invention relates to a preparation method of composite cavity microfibers based on a micro-fluidic technology. The preparation method is characterized in that in the preparation process of cavitymicrofibers, a modified material capable of promoting the cell wall adhesion growth is introduced in a microfiber inner cavity; while the cavity is formed, the modified material is adhered onto the cavity to form a modified coating layer, so that a promoting effect on late cell adhesion and culture is provided. By utilizing the micro-fluidic technology, a micron-sized channel capable of generatinga coaxial laminar flow pattern is formed, the flow pattern control on a sample fluid is realized, and the sample fluid is finally solidified into a micron-sized hollow fiber material with a specificinner coating structure. The microfiber material can simulate a microstructure in a human body tissue, and a new method and a new concept are provided for tissue engineering and organ regeneration. The preparation method provided by the invention is simple and reliable to operate, high in efficiency and excellent in technical effect; convenient conditions are provided for the modification of the microfibers; an internal finish coating is uniform, stable, simple and controllable to facilitate the cell wall adhesion growth.
Year: 2018
Country: CN
Doc No: 108149342