23 Jul Preparation method of cartilage repair scaffold material
Abstract
The invention relates to the technical field of tissue engineering scaffolds, and in particular relates to a preparation method of a cartilage repair scaffold material. The preparation method comprises the following steps: firstly, preparing chitosan nano fibers containing hydroxyapatite by virtue of electrostatic spinning; then, packing by using hyaluronic acid; finally, preparing the cartilage repair scaffold material by virtue of a freeze-drying experimental method. The cartilage repair scaffold material obtained by the preparation method disclosed by the invention has a relatively large specific area and is favorable for cartilage cells to grow and proliferate; hydroxyapatite serves as the main component in a human bone to provide a lot of necessary raw materials for the growth of the cartilage cells; hyaluronic acid is the main component of cartilage liquid and is favorable for providing a good growth environment for the cartilage cells; meanwhile, the hyaluronic acid can be compounded with chitosan to package nano hydroxyapatite in chitosan so as to form a sustained-release system of hydroxyapatite; growth factors can be used for promoting rapid proliferation of the cartilage cells.
Year: 2014
Country: CN
Doc No: 103690991