23 Jul Preparation method of bionic cartilage extracellular matrix for tissue engineering
Abstract
The invention discloses a preparation method of a bionic cartilage extracellular matrix for tissue engineering, which comprises the following steps of: selecting a raw material having the same main components as the normal articular cartilage extracellular matrix as a bionic raw material to prepare the bionic cartilage extracellular matrix for the tissue engineering; fully dissolving the selectedbionic raw material in organic acid; and then carrying out hole making processing, curing processing and strengthening processing in sequence to the selected bionic raw material. The method makes thematerial structure of the finally obtained bionic cartilage extracellular matrix for the tissue engineering have physical structure characteristics suitable for biological behavior requirements such as vaccination, survival, multiplication and the like of a cartilage seed cell and have good biocompatibility, appropriate degradation rate and biomechanical strength at the same time. The preparationmethod has the advantages of wide material source, low cost, simple and easy process and good reproducibility, and the prepared product can be widely used to repair a large area of articular cartilage defect and has fewer clinical complications.
Year: 2010
Country: CN
Doc No: 101690830