23 Jul Preparation method of asymmetric porous membrane based on electrostatic spinning technology
Abstract
The invention provides a preparation method of an asymmetric porous membrane based on electrostatic spinning technology. The preparation method comprises the following steps of: (1) dissolving one or more polymers in a corresponding solvent to obtain a spinning solution of certain concentration; (2) carrying out electrostatic spinning with the spinning solution and receiving with common non-woven fabric to prepare a double-layer fiber membrane; (3) preparing a crosslinking solution with a certain ratio from one or more solvents, and placing in a specific container; and (4) covering the specific container with the double-layer fiber membrane, sealing the whole device with the membrane material while ensuring that the electrospun nano fiber layer faces the crosslinking solution, and carrying out fumigation crosslinking at 10-250 DEG C for 0-5h to obtain the asymmetric porous membrane. According to the preparation method, the nano fiber layer undergoes gradient crosslinking to obtain the porous membrane with asymmetric functional layers; and the average pore diameter of the porous membrane is easily adjustable in the range of 20-3000nm. The preparation method is simple in preparation process and low in equipment requirement; and the prepared porous membrane has high flux and good retention performance, and can be applied to the fields of membrane separation, tissue engineering, cell culture, wound dressings, cell diaphragms and the like.
Year: 2016
Country: CN
Doc No: 105536579