23 Jul Preparation method of antimicrobial bacterial cellulose material
Abstract
The invention relates to a preparation method of an antimicrobial bacterial cellulose material. The method comprises the following steps: adding an organosilicon quaternary ammonium salt into a solvent to obtain an organosilicon quaternary ammonium salt solution; and adding the organosilicon quaternary ammonium salt solution into a bacterial cellulose hydrogel, regulating the pH value to 2.0-7.0, carrying out stirring or oscillating reaction at 5-95 DEG C for 24-72 hours, and cleaning. The method is simple to operate and mild in conditions; and the grafting reaction occurs on the fiber surface, so that the grafting ratio is high. The graft-modified bacterial cellulose material has the advantages of bacterial resistance, protein adsorptivity, cell adhesion promotion characteristic, and specific pH responsivity and temperature responsivity. The antimicrobial bacterial cellulose material has excellent resistance to Staphylococcus aureus and other bacteria, is beneficial to adhesion and growth of the cells in the material, and enhances the application potential of the bacterial cellulose material in the fields of antimicrobial wound dressings, intelligent responsive drug-slow-release carriers, tissue engineering stent biomedicine and the like.
Year: 2016
Country: CN
Doc No: 105860121