23 Jul Preparation method for protein-polyose-polylactic acid polycaprolactone vascular stent
Abstract
The invention relates to a preparation method for a protein-polyose-polylactic acid polycaprolactone vascular stent. The method comprises the following steps: (1) completely dissolving chitosan into a hexafluoroisopropanol and trifluoroacetic acid mixed solution to obtain a chitosan solution; (2) completely dissolving collagen into hexafluoroisopropanol to obtain a collagen solution; (3) completely dissolving polylactic acid polycaprolactone into hexafluoroisopropanol to obtain a polylactic acid polycaprolactone solution; and (4) mixing and stirring the chitosan solution, the collagen solution and the polylactic acid polycaprolactone solution to obtain a protein-polyose-polylactic acid polycaprolactone spinning solution, and then achieving static spinning to obtain the protein-polyose-polylactic acid polycaprolactone vascular stent. The prepparation materials have superior biocompatibility and mechanical property; and the designed multi-component composite biological material has a broad application prospect, and the preparation method is simple and feasible and is mainly used in small-caliber vascular tissue engineering.
Year: 2013
Country: CN
Doc No: 103147225