23 Jul Preparation method for easy-suturing high-simulation tissue engineering neural repair scaffold
Abstract
The invention relates to a preparation method for an easy-suturing high-simulation tissue engineering neural repair scaffold. The preparation method comprises a step of preparing suspension, a step ofpreparing an array micro-pipe inner core, a step of preparing collagen outer skin and a step of cutting and assembling. The step of preparing the suspension comprises the following steps: weighing collagen and chitosan, after uniformly mixing, and dissolving in acetic acid solution. The step of preparing the array micro-pipe inner core comprises the following steps: enabling the suspension to beinjected in a mould, inserting a temperature conducting rod, immerging in liquid nitrogen and performing gradient cooling, freeze-drying, crosslinking, washing, freeze-storing and freeze-drying again.The step of preparing the collagen outer skin comprises the following steps: enabling the suspension to be injected in the mould, washing, drying, crosslinking, washing again, freeze-storing and drying again. The step of cutting and assembling comprises the following steps: cutting and assembling. The provided rational preparation method is capable of solving problems of an existing scaffold product that an internal three-dimensional structure is lacked and the collapse is easy, and solving a problem that the parallel and level tail end of the porous scaffold is not easily sutured.
Year: 2018
Country: CN
Doc No: 108714247