Preparation method for composite hydrogel

Preparation method for composite hydrogel

Abstract

The invention discloses a preparation method for composite hydrogel and belongs to the technical field of polymers. The preparation method comprises the following steps: firstly, preparing hydroxyapatite (HA) and chitosan (CS) into solution; secondly, doping the solution in a polyacrylamide (PAM) network structure. According to the preparation method, the preparation process is simple and convenient to operate and the cost is reduced; besides, the obtained material overcomes the defects that a CS stent is easily bent and is poor in mechanical property, and retains good mechanical properties of tensile strength and compression resistance endowed by the HA; in the preparation process, the HA and the CS which have good biocompatibility are doped in the PAM network structure, and good mechanical properties are endowed for a hydrogel material. Therefore, the composite material can be used as a replacement material of cartilage and has potential application value in the tissue engineering.

Year:  2014

Country:  CN

Doc No:  104189960

 

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