23 Jul Preparation method and application of antibacterial repair type electrostatic spinning collagen-bacterial cellulose composite nanofiber scaffold
Abstract
The invention discloses a preparation method of an antibacterial repair type electrostatic spinning collagen-bacterial cellulose composite nanofiber scaffold. The method comprises the following steps: preparing a mixed solvent, dissolving bacterial cellulose and collagen, preparing a bacterial cellulose and collagen mixed solution containing AgNO3 or gold and silver nanocluster, spinning the bacterial cellulose and collagen mixed solution containing AgNO3 or gold and silver nanocluster and other fluorescent nanomaterials by adopting an electrostatic spinning technology, and reducing a composite fiber containing the AgNO3 or gold and silver nanocluster to obtain a nanofiber scaffold containing the nano-silver or gold and silver fluorescent nanomaterials by adopting ultraviolet light illumination, wherein the related composite nanofiber scaffold is used for cell culture to prepare a tissue engineering material. Different bacterial celluloses and collagens are proportioned, and the prepared composite nanofiber scaffold realizes adjustable mechanical strength and in-vivo degrading capability and can be used for preparing tissue engineering materials of multiple purposes.
Year: 2014
Country: CN
Doc No: 103751848